During the past 20 years, Dr Eric Daiter has successfully helped thousands of couples that have suffered through the grief and emotional trauma of a pregnancy loss. If you have questions about miscarriage or you just want to find a compassionate infertility specialist to guide you, Dr Eric Daiter would be happy to help (in his Edison, NJ office or on the telephone). It is easy, just call us at 908 226 0250 to set up an appointment (leave a message with your name and number if we are unable to get to the phone and someone will call you back).
"I always try to be available for my patients since I do understand the pain and frustration associated with fertility problems or endometriosis."
"I understand that the economy is very tough and insurance companies do not cover a lot of the services that might help you. I always try to minimize your out of pocket cost while encouraging the most successful and effective treatments available."
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Luteal Progesterone (Pulsatile)
Circulating progesterone concentrations for any given woman are pulsatile during the luteal phase of the menstrual cycle (from ovulation until the onset of menses). Therefore, a single random progesterone concentration during the luteal phase (which is a commonly ordered blood test) may be misleading since it may have been drawn at the peak or the nadir of a pulse.
Many reproductive endocrinologists believe that the histologic (microscopic) appearance of the endometrium (lining of the uterus) obtained by endometrial biopsy is far more accurate in assessing progesterone insufficiency. It is the progesterone effect on the lining of the uterus (which depends on the concentration of progesterone hormone as well as the progesterone receptor concentration within the endometrial tissue) rather than the progesterone concentration in the blood that is of reproductive importance. For example, high progesterone concentrations may have minimal effect on the lining of the uterus if the progesterone receptor concentrations in this tissue are low. Similarly, low progesterone concentrations may have a normal effect on the lining of the uterus if the progesterone receptor concentrations in this tissue are high.
These graphs are based upon data collected by Dr. Michael R. Soules and shows that progesterone concentrations obtained every 15 minutes for a day from the same (normally cycling) woman in the mid luteal phase (left) and the late luteal phase (right) may vary tremendously, with many of the values being “abnormally low.”